A new peritoneal carcinomatosis model in cyclosporine immunosuppressed rats.
نویسندگان
چکیده
Colorectal cancer (CRC) cells (HT29) were injected into the intraperitoneal (i.p.) cavity of immunosuppressed male Sprague Dawley rats. Immunosuppression was achieved via a daily i.p. injection of cyclosporine 35 mg/kg/day. Three groups of rats (n = 6 per group) were injected with 20, 50 or 100 million HT29 cells. All animals developed tumours indicating that this animal model may prove useful for future research in human colorectal carcinomatosis.
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عنوان ژورنال:
- Anticancer research
دوره 28 1A شماره
صفحات -
تاریخ انتشار 2008